The Disrupt 50
An index of the top private innovators shaping the future of tech and pushing the boundaries of human achievement.
Innovator Spotlight: OpenEvidence
OpenEvidence is a leading AI-powered clinical decision support platform that delivers instant, evidence-based answers to verified physicians at the point of care. Drawing from authoritative sources and medical journals, the platform synthesizes vast medical literature into clear, actionable insights via a secure, HIPAA-compliant chatbot and mobile apps.
In an industry overwhelmed by rapidly doubling medical knowledge and persistent physician shortages, OpenEvidence disrupts traditional static references by deploying agentic AI agents capable of autonomous, cross-referenced research. Recent momentum underscores its traction: the company hit one million clinical consultations in a single day in March 2026 and expanded EHR integrations such as Mount Sinai’s Epic system. While legacy competitors like UpToDate and Elsevier’s ClinicalKey AI provide established but less dynamic resources, OpenEvidence’s rapid adoption signals a broader industry pivot toward embedded, generative AI tools. The tools promise to boost accuracy, reduce cognitive load, and drive workflow efficiency.
Looking forward, OpenEvidence envisions “medical super-intelligence” through multimodal, specialist AI agents that not only answer queries but uncover novel connections across literature, ultimately freeing clinicians for higher-value patient care. As healthcare accelerates integration of AI directly into clinical workflows, the company is well-positioned to lead this transformation against intensifying competition.
Deal Metrics
Median
Recent Deal Size
$1.0B
Average
Recent Deal Size
$10.8B
Median
Raised to Date
$1.6B
Average
Raised to Date
$9.8B
Median
Time Between Financing Rounds
0.7 years
Average
Time Between Financing Rounds
1.0 years
Top Disrupt 50 Investors
Andreessen Horowitz
Menlo Park, CA
Sequoia Capital
Menlo Park, CA
Nvidia (NAS: NVDA)
Santa Clara, CA
Coatue Management
New York, NY
DST Global
George Town, Cayman Islands
General Catalyst
San Francisco, CA
Lightspeed Venture Partners
Menlo Park, CA
Octant Ventures
San Francisco, CA
Thrive Capital
New York, NY
The Disrupt 50
Tap any company for additional details.
| Rank | Rank Move | Company | Post Money | Expand row | |||
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| 1 | SpaceX | $1,250.0B |
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Industry
Space Technology
Recent Deal
February 2026
Value Trend
Company DescriptionSpaceX is drastically lowering the cost of space travel and access by pioneering reusable rockets and vertically integrated manufacturing. Recent NewsSpaceX successfully launched Starship V3 on May 22, 2026, achieving orbital deployment with the most powerful rocket ever built. In late May 2026, the U.S. Space Force awarded the company a $4.16 billion contract for a space-based system to track airborne targets. Additionally, the Artemis 2 mission launched on April 2, 2026, marking the first crewed lunar flight in over five decades. Recent FinancingSpaceX confidentially filed for a record-breaking IPO on April 1, 2026 (targeting ~$1.75T valuation), following its earlier all-stock merger with xAI. The listing is supported by banks including Bank of America, Citigroup, and Goldman Sachs. Pending FinancingSpaceX has confidentially filed for an initial public offering on the Nasdaq targeted for June 12, 2026, and holds a $60 billion option to acquire the AI startup Cursor in July 2026. |
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| 2 | Anthropic | $965.0B |
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Industry
Artificial Intelligence
Recent Deal
May 2026
Value Trend
Company DescriptionAnthropic is an AI research company developing highly capable and safe artificial intelligence systems. Recent NewsAnthropic released Claude Opus 4.8 on May 28, 2026, featuring improved performance for coding and professional workflows. On May 19, 2026, the company announced a strategic alliance with KPMG to integrate its AI models across KPMG’s global workforce of over 276,000 employees. Additionally, Anthropic expanded its European presence by opening a new office in Milan on May 27, 2026. Recent FinancingAnthropic secured $65 billion in Series H venture funding led by Dragoneer Investment Group, Greenoaks Capital Partners, and Sequoia Capital. Pending FinancingAnthropic has officially and confidentially filed for an initial public offering on the U.S. stock market as of June 1, 2026. |
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| 3 | OpenAI | $852.0B |
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Industry
Artificial Intelligence
Recent Deal
March 2026
Value Trend
Company DescriptionOpenAI develops powerful artificial intelligence models that fundamentally change how people and computers interact and create. Recent NewsOn April 23, 2026, OpenAI unveiled its newest frontier model, GPT-5.5, followed by the announcement of an expanded partnership with Amazon Web Services on April 28 to integrate its models into the Bedrock platform. The company also amended its partnership with Microsoft on April 27, 2026, a move that ended Microsoft’s revenue share and granted OpenAI the flexibility to serve products through any cloud provider. Concurrently, a high-stakes civil trial involving co-founder Elon Musk proceeded in late April 2026, centering on the organization’s founding principles and commercial transition. Recent FinancingOpenAI raised venture funding in a round led by Nvidia, SoftBank Group, and Amazon.com. Pending FinancingOpenAI is reportedly seeking U.S. government loan guarantees to support a $1 trillion infrastructure buildout and is rumored to be considering an initial public offering at a $1 trillion valuation. |
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| 4 | Stripe | $159.0B |
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Industry
Fintech
Recent Deal
February 2026
Value Trend
Company DescriptionStripe offers an easy and intuitive platform for businesses to manage and process online payments, disrupting traditional banking methods for e-commerce. Recent NewsOn April 29, 2026, Stripe launched a suite of agentic commerce tools, including a new Link wallet that allows AI agents to make secure payments using one-time-use cards. The company also announced a partnership with Google on April 30, 2026, to allow businesses to sell products within the Gemini app and introduced real-time streaming payments for AI-native businesses. Additionally, Stripe launched a new checkout experience for Facebook on March 24, 2026, to optimize cross-platform payment processing. Recent FinancingThe company completed a secondary transaction with Thrive Capital, Coatue Management, and Andreessen Horowitz to provide liquidity to employees and repurchase shares. Pending FinancingStripe is reportedly considering an acquisition of all or part of PayPal, though discussions are in the early stages and an agreement is not certain. |
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| 5 | Databricks | $134.0B |
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Industry
Data Intelligence
Recent Deal
December 2025
Value Trend
Company DescriptionDatabricks offers a unified data platform built on the open-source Apache Spark framework that allows organizations to combine their data engineering, data science, and machine learning workflows. Recent NewsOn March 24, 2026, Databricks expanded into the cybersecurity market with the launch of Lakewatch, an open, agentic SIEM platform designed for the AI era. The company also announced the general availability of Genie Code on March 11, 2026, introducing agentic engineering capabilities to data workflows. Additionally, on May 31, 2026, Databricks launched copy-on-write database branching in Lakebase to eliminate developer bottlenecks by enabling instant, production-scale database branches. Recent FinancingDatabricks secured an estimated $4 billion in Series L venture funding with Insight Partners, J.P. Morgan Growth Equity Partners, and Fidelity Management & Research Company as lead investors. Pending FinancingDatabricks is preparing for a potential initial public offering in 2026 as it optimizes its capital structure. |
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| 6 | Waymo | $126.0B |
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Industry
Autonomous Driving
Recent Deal
February 2026
Value Trend
Company DescriptionWaymo develops and operates a fleet of fully autonomous vehicles that provide commercial ride-hailing services without a human driver, aiming to replace traditional transportation models with automated technology. Recent NewsOn May 28, 2026, Waymo introduced the Ojai, its first purpose-built robotaxi developed with Zeekr, offering free rides to select passengers in San Francisco, Phoenix, and Los Angeles. Previously, the company suspended all freeway operations on May 22, 2026, following safety concerns that led to a voluntary software recall of over 3,000 vehicles earlier that month due to navigation issues in flooded conditions. Recent FinancingWaymo secured $16 billion in venture funding led by Dragoneer Investment Group, DST Global, and Sequoia Capital. Pending FinancingWaymo's fleet operations partner, Moove, is reportedly close to finalizing an oversubscribed $1.2 billion debt financing round to support the rollout of autonomous vehicles. |
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| 7 | Revolut | $100.0B |
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Industry
Financial Technology
Recent Deal
February 2026
Value Trend
Company DescriptionRevolut is a global financial technology company that provides a mobile-based platform for digital banking, foreign exchange, and multi-currency payment services to replace traditional banking infrastructure. Recent NewsOn March 5, 2026, Revolut submitted an application for a U.S. national bank charter to facilitate the direct offering of personal loans and insured deposits. More recently, the company introduced an AI assistant on April 9, 2026, followed by the launch of GlobalHire on April 15, 2026, to support international expansion for its business customers. Recent FinancingThe company completed a secondary share sale led by Coatue, Greenoaks, and Dragoneer. Pending FinancingRevolut is reportedly considering a secondary share sale in late 2026 and plans to pursue an initial public offering by 2028. |
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| 8 | Anduril Industries | $61.0B |
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Industry
Defense Technology
Recent Deal
May 2026
Value Trend
Company DescriptionAnduril Industries builds autonomous defense systems and software to rapidly modernize and deliver capabilities for military applications. Recent NewsOn April 30, 2026, Anduril Industries announced the addition of 5G communications to its Sentry family of systems to enhance tactical networking and connectivity. During April 2026, the company also formed a partnership with Kraken Technology Group to build unmanned military boats and saw the U.S. Air Force begin experimental testing of its YFQ-44A Fury fighter jet. Additionally, on March 11, 2026, Anduril reached an agreement to acquire ExoAnalytic Solutions to accelerate its space domain awareness and missile defense capabilities. Recent FinancingAnduril Industries secured $5 billion in Series H venture funding led by Andreessen Horowitz and Thrive Capital, with participation from Coral Capital. Pending FinancingAnduril Industries is reportedly planning an initial public offering for 2026 or 2027, though a spokesperson stated that a listing is not yet imminent. |
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| 9 | Cursor | $52.0B |
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Industry
Software Development
Recent Deal
April 2026
Value Trend
Company DescriptionAnysphere is developing an AI-powered operating system for software development that fundamentally changes how developers interact with code. Recent NewsIn late April 2026, a Cursor AI agent autonomously deleted the entire production database and backups of the startup PocketOS in just nine seconds after encountering a credential mismatch. On April 29, 2026, the company released the Cursor SDK, a programmatic tool allowing engineers to integrate its agent runtime directly into software delivery pipelines. Previously, on April 2, 2026, the company launched Cursor 3, which introduced a unified workspace for building software using autonomous agents. Recent FinancingCursor is in a major collaboration with SpaceX, which includes an option for SpaceX to acquire it for $60 billion (or pay $10B for work) within the next year, following prior funding rounds led by Andreessen Horowitz, Thrive, and Nvidia participation." Pending FinancingSpaceX is rumored to be pursuing a $60 billion acquisition of Cursor following its planned initial public offering in June 2026. |
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| 10 | Ripple | $40.0B |
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Industry
Blockchain Payments
Recent Deal
November 2025
Value Trend
Company DescriptionRipple offers a protocol using blockchain technology to modernize and streamline inefficient and costly cross-border payment systems between banks. Recent NewsOn March 23, 2026, Mastercard launched a blockchain payment initiative featuring Ripple as a key partner to integrate digital asset technology into traditional financial infrastructure. In early May 2026, Ripple collaborated with JPMorgan and Mastercard to successfully complete the first cross-border tokenized U.S. treasury settlement. Furthermore, pilot results shared on April 10, 2026, showed that Japanese banks achieved 60 percent cost savings by utilizing Ripple for international payment processing. Recent FinancingThe company secured $500 million in venture capital from Citadel Securities, Fortress Investment Group, and Galaxy Digital, along with C1 Fund. Pending FinancingRipple is reportedly engaged in ongoing discussions regarding a potential initial public offering, though no specific timeline or valuation has been finalized. |
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| 11 | Figure AI | $39.0B |
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Industry
Humanoid Robotics
Recent Deal
May 2025
Value Trend
Company DescriptionFigure AI is developing general-purpose humanoid robots designed to assist with everyday tasks in unpredictable environments using advanced artificial intelligence. Recent NewsOn May 26, 2026, Figure AI announced a commercial partnership with Catalyst Brands to deploy its humanoid robots for automating sorting and packing tasks at a distribution center in Nevada. Earlier in May 2026, the company shared results from a 200-hour autonomous stress test where its F.03 robots successfully sorted nearly 250,000 packages. Additionally, on April 29, 2026, the company announced it was ramping up production of the Figure 03 model to meet industrial demand. Recent FinancingFigure AI secured $1.5 billion in Series C venture funding, led by Parkway Venture Capital, with participation from Intel Capital and Microsoft. Pending FinancingAs of May 2026, rumors suggest that Figure AI is exploring an additional $1.5 billion funding round that could increase its valuation to $39.5 billion. |
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| 12 | Project Prometheus | $38.0B |
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Industry
Physical AI
Recent Deal
April 2026
Value Trend
Company DescriptionProject Prometheus develops "physical AI" systems focused on engineering, manufacturing, and industrial applications in sectors like computers, automobiles, aerospace, and spacecraft. Recent NewsProject Prometheus recruited xAI co-founder Kyle Kosic in May 2026 to lead its AI infrastructure projects. The startup also expanded its London office that same month by hiring quant researcher Andrei Margeloiu from Citadel. Reports from April 2026 indicate the company has scaled to approximately 200 employees and is focusing on developing physical AI to automate industrial sectors such as aviation and chip manufacturing. Recent FinancingProject Prometheus is in talks to raise an undisclosed amount of venture funding from BlackRock and JP Morgan Chase. Pending FinancingProject Prometheus is reportedly considering establishing a separate holding company structure and expanding its funding pool by tens of billions of dollars, potentially up to $100 billion, to acquire industrial businesses that can be reshaped by physical AI. |
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| 13 | Ramp | $32.0B |
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Industry
Fintech
Recent Deal
November 2025
Value Trend
Company DescriptionRamp uses AI to streamline corporate spending management, helping businesses automate finance tasks and save money and time. Recent NewsOn April 29, 2026, Ramp launched a fleet of AI agents designed to automate the procurement process, including vendor sourcing and contract reviews. The company also announced a multi-year partnership with Stanford Athletics on May 26, 2026, to serve as its official expense management partner. Additionally, in May 2026, the startup Midday joined Ramp to integrate its financial software design into the platform. Recent FinancingRamp secured $300 million of venture funding from Lightspeed Ventures, Coatue Management, and Avenir Growth Capital. Pending FinancingRamp is reportedly in advanced talks to raise $750 million at a valuation exceeding $40 billion, with existing backers GIC and Iconiq Capital expected to co-lead the round. |
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| 14 | Safe Superintelligence | $32.0B |
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Industry
Artificial Intelligence
Recent Deal
April 2025
Value Trend
Company DescriptionSafe Superintelligence develops extremely powerful artificial intelligence systems by prioritizing safety and long-term research over immediate commercial demands. Recent NewsIn early February 2026, senior software engineer Shahar Papini left the company to co-found a new startup focused on AI verification. Reports from April 2026 highlight the company's continued focus on a research-centric business model that prioritizes safety over immediate commercial products or revenue. Additionally, the company has grown to approximately 40 employees while developing new scientific principles to address limitations in current large language models. Recent FinancingSafe Superintelligence secured $2 billion in venture funding from Greenoaks Capital Partners, Nvidia, and Lightspeed Venture Partners. Pending FinancingSafe Superintelligence is reportedly in the process of raising an additional $2 billion in funding at a valuation exceeding $32 billion. |
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| 15 | VAST Data | $30.0B |
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Industry
AI Infrastructure
Recent Deal
February 2026
Value Trend
Company DescriptionVAST Data provides a unified software platform that integrates storage, database, and computing functions to replace traditional hard drives with high-performance flash infrastructure for large-scale artificial intelligence workloads. Recent NewsOn March 16, 2026, VAST Data announced the availability of VAST Foundation Stacks, a library designed to streamline the adoption of NVIDIA Blueprints for enterprise AI pipelines. Additionally, on February 25, 2026, the company introduced Polaris, a global control plane for orchestrating AI data infrastructure across hybrid multicloud environments, and unveiled a new computing platform for agentic AI systems. Recent FinancingAn undisclosed investor reached an agreement to sell a 3.33% stake in the company for $1 billion. Pending FinancingVAST Data is reportedly preparing for a potential initial public offering, with CEO Renen Hallak indicating the company expects to be ready for a debut as early as the end of 2026. |
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| 16 | Motional | $28.2B |
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Industry
Autonomous Vehicles
Recent Deal
August 2025
Value Trend
Company DescriptionMotional develops and deploys advanced, fully driverless vehicles to bring autonomous ride-hailing services to market. Recent NewsOn March 13, 2026, Motional and Uber relaunched a commercial robotaxi service in Las Vegas, deploying all-electric IONIQ 5 vehicles to riders at key locations including the Strip and Downtown. Additionally, in late March 2026, the company's leadership detailed a strategic shift toward licensing its autonomous technology to other mobility platforms to ensure more cost-effective and scalable deployments. Recent FinancingThe company received KRW 629.1 billion in venture funding from Hyundai Motors Group. Pending FinancingMotional is reportedly seeking additional capital after its co-parent, Aptiv, announced it would stop funding the venture. |
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| 17 | Reflection AI | $27.5B |
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Industry
Artificial Intelligence
Recent Deal
May 2026
Value Trend
Company DescriptionReflection AI develops autonomous agents and open-source models designed to automate the complete software engineering lifecycle, including code comprehension, debugging, and system design. Recent NewsOn May 26, 2026, Reflection AI established a policy and lobbying operation in Washington, D.C., to advocate for open-source AI as a national security imperative. The company also reached a deal with the Pentagon on May 1, 2026, to integrate its technology into classified computer networks. Previously, on March 16, 2026, Reflection AI partnered with the Shinsegae Group to build a 250-megawatt AI factory in South Korea. Recent FinancingReflection AI is securing $2.5 billion in Series C venture funding from Disruptive. |
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| 18 | Cognition | $26.0B |
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Industry
AI Software
Recent Deal
May 2026
Value Trend
Company DescriptionCognition develops artificial intelligence tools designed to independently plan and execute complex software engineering tasks. Recent NewsOn May 28, 2026, Cognition announced a strategic partnership with Fiserv to deploy its AI software engineer, Devin, to accelerate the modernization of core banking technology. Additionally, on May 21, 2026, the company launched a new capability allowing Devin to build, run, and test software natively within Windows virtual machines. Recent FinancingCognition secured Series D venture funding in a round led by 8VC, Lux Capital, and General Catalyst. |
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| 19 | Epic Games | $22.5B |
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Industry
Video Games
Recent Deal
November 2024
Value Trend
Company DescriptionEpic Games develops popular video games and provides the foundational creation software and digital storefront used by developers to build and distribute interactive content under more favorable financial terms than traditional platforms. Recent NewsIn early April 2026, Epic Games reportedly initiated layoffs of over 1,000 employees following a significant downturn in Fortnite engagement. On April 30, 2026, the company launched a major v40.30 update for Fortnite, introducing several new modes and maintenance schedules. Additionally, on May 4, 2026, Apple filed an emergency application with the Supreme Court to stay a mandate related to App Store commissions in its ongoing legal battle with Epic Games. Recent FinancingEpic Games secured $1.5 billion in venture funding in a round led by The Walt Disney with participation from Qatar Investment Authority and Insight Capital Partners. Pending FinancingDisney executives are reportedly considering a full acquisition of Epic Games following their prior $1.5 billion investment. |
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| 20 | Kalshi | $22.0B |
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Industry
Financial Exchange
Recent Deal
March 2026
Value Trend
Company DescriptionKalshi is an event contract exchange platform that allows users to trade on the outcome of future real-world events. Recent NewsOn May 29, 2026, Kalshi launched the first regulated bitcoin perpetual futures contract in the United States after receiving historic clearance from the Commodity Futures Trading Commission. Throughout late May 2026, the company engaged in multiple legal battles across Wisconsin, Minnesota, and Rhode Island to protect its federal jurisdiction against state gaming regulators. Additionally, the platform expanded its surveillance capabilities in May 2026 by appointing a former FBI analyst to oversee market integrity. Recent FinancingKalshi raised over $1 billion in a funding round led by Coatue Management, following previous rounds led by Paradigm and Sequoia Capital. |
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| 21 | Perplexity AI | $20.0B |
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Industry
Artificial Intelligence
Recent Deal
September 2025
Value Trend
Company DescriptionPerplexity AI is an AI-powered search engine that delivers direct, cited, and conversational answers to user queries, fundamentally changing how information is retrieved online. Recent NewsOn May 28, 2026, CNN filed a lawsuit against Perplexity AI in the Southern District of New York, alleging the company unlawfully scraped and distributed thousands of copyrighted stories and videos. Perplexity expanded its product offerings by making its Personal Computer tool available for all Mac users on May 11, 2026, and integrating its search capabilities into Microsoft 365 apps on May 29, 2026. Additionally, in late May 2026, the company distributed Mac Minis to tech creators to promote its new local agentic computing features. Recent FinancingThe company secured a $1.4 billion Series C funding round with major participation from SoftBank Group, NVentures (NVIDIA), and Macquarie Capital. Pending FinancingPerplexity AI is reportedly in early talks to raise between $500 million and $1 billion in a new funding round that would value the company at approximately $18 billion. |
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| 22 | Kraken | $20.0B |
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Industry
Cryptocurrency Exchange
Recent Deal
November 2025
Value Trend
Company DescriptionKraken is a major global platform that allows users to buy, sell, and trade a wide variety of digital assets and cryptocurrencies. Recent NewsIn April 2026, Kraken announced its intent to acquire the derivatives exchange Bitnomial for up to $550 million to expand its regulated trading offerings in the United States. During the same month, the company released financial disclosures reporting $2.2 billion in revenue for the 2025 fiscal year, a 33 percent increase over the previous year. Additionally, the company’s Wyoming-chartered bank, Kraken Financial, was granted a Federal Reserve master account by the Federal Reserve Bank of Kansas City earlier in the spring of 2026. Recent FinancingKraken secured $800 million in Series C venture funding, with the deal led by Jane Street, Oppenheimer Partners, and Tribe Capital. Pending FinancingKraken has reportedly suspended its plans for an initial public offering as of March 2026 due to market uncertainty and declining crypto prices. |
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| 23 | Helsing | $18.0B |
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Industry
Defense Technology
Recent Deal
May 2026
Value Trend
Company DescriptionHelsing develops artificial intelligence software and autonomous hardware, such as drones, to process sensor data and provide real-time battlefield insights for democratic military forces. Recent NewsOn May 19, 2026, Helsing and OHB established a joint venture named KIRK to develop tactical space-based reconnaissance systems. Additionally, the company expanded its European operations by opening a new office in Stockholm on April 19, 2026, to strengthen its commitment to Swedish and Nordic defense. Recent FinancingHelsing is reportedly raising venture funding in a deal led by Dragoneer Investment Group and Lightspeed Venture Partners. Pending FinancingHelsing is reportedly in advanced talks to raise $1.2 billion in venture funding led by Dragoneer Investment Group and Lightspeed Venture Partners, which would value the company at approximately $18 billion. |
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| 24 | Deel | $17.3B |
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Industry
HR Technology
Recent Deal
October 2025
Value Trend
Company DescriptionDeel provides a unified platform that automates the legal and financial complexities of hiring, paying, and managing a global workforce by acting as the employer of record in over 150 countries. Recent NewsOn March 20, 2026, the High Court set aside the joining of three Deel executives as defendants in an industrial espionage lawsuit brought by competitor Rippling. Deel later acknowledged on March 26, 2026, that it made a payment to a former Rippling employee involved in the case but denied allegations of seeking confidential information. Furthermore, on April 29, 2026, the company released findings indicating that AI trainer roles are its fastest-growing cross-border positions, experiencing a 283 percent increase in hiring. Recent FinancingDeel completed a $300 million Series E funding round and a $300 million secondary share sale with participation from Ribbit Capital, Andreessen Horowitz, and Coatue Management. Pending FinancingDeel is reportedly undergoing leadership changes and strengthening its governance as part of preparations for a potential initial public offering that could occur as early as 2026. |
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| 25 | Rippling | $16.8B |
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Industry
Workforce Management
Recent Deal
May 2025
Value Trend
Company DescriptionRippling offers a single, unified platform that automates HR, IT, and finance, allowing businesses to manage everything from payroll to device setup for their global workforce in one system. Recent NewsOn May 27, 2026, Rippling opened its expanded European headquarters in Dublin and announced plans to add 150 new jobs to its Irish workforce over the next year. Previously, the company launched Automated Compliance on April 28 to streamline SOC 2 audit readiness and introduced Rippling AI on March 18 to automate tasks across human resources, IT, and finance departments. Recent FinancingThe company secured $460 million in Series G venture funding from Goldman Sachs Growth Equity, Elad Gil, and Dubin & Co. The capital will be used for market expansion, product enhancements, and new product development. |
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| 26 | Sierra | $15.8B |
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Industry
Conversational AI
Recent Deal
May 2026
Value Trend
Company DescriptionSierra provides AI technology that enables businesses to create more human-like and effective customer experiences. Recent NewsOn May 28, 2026, Sierra expanded its international presence by opening a new office in Toronto. During March and April 2026, the company launched Ghostwriter, a tool for autonomously building AI agents, and introduced its first Level 1 PCI-compliant payment capability to enable secure transactions within AI-driven conversations. Recent FinancingSierra secured $950 million in a blend of equity and debt funding led by Tiger Global Management and GV, with participation from Benchmark Capital Holdings. Pending FinancingSierra is reportedly nearing a deal for a $350 million financing round that would value the startup at $10 billion. |
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| 27 | Veeam | $15.0B |
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Industry
Data Protection
Recent Deal
December 2024
Value Trend
Company DescriptionVeeam provides software that automates the backup, recovery, and management of data across virtual, physical, and cloud-based environments to ensure business continuity and resilience against cyber threats. Recent NewsOn May 12, 2026, Veeam launched the DataAI Command Platform and a Data and AI Trust Maturity Model to provide unified infrastructure for data and AI trust. Earlier, on March 12, 2026, the company issued critical security patches to address multiple remote code execution vulnerabilities found in its Backup and Replication software. Additionally, on April 28, 2026, market reports identified Veeam as the top-ranked data protection software provider globally for the second half of 2025. Recent FinancingVeeam completed a $2 billion secondary equity offering and received a strategic investment from Microsoft, with participation led by TPG, Temasek, and Neuberger Berman Capital Solutions. Pending FinancingVeeam is currently preparing for an initial public offering, which is rumored and expected to occur as early as late 2025 or 2026. |
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| 28 | Applied Intuition | $15.0B |
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Industry
Autonomous Vehicle Software
Recent Deal
June 2025
Value Trend
Company DescriptionApplied Intuition provides software and AI stacks to help manufacturers develop, validate, and deploy autonomous driving and advanced driver-assistance systems for vehicles across multiple industries. Recent NewsOn May 14, 2026, Applied Intuition was selected by the Department of War's CDAO to build the software platform for its Autonomy Factory program to accelerate the fielding of autonomous systems. The company also announced a collaboration with Heidelberg Materials on April 30, 2026, to deploy autonomous haulage systems at a quarry in Australia. Additionally, Applied Intuition signed a strategic memorandum of understanding with HII on April 21, 2026, to advance AI-defined warship capabilities for the U.S. Navy and its allies. Recent FinancingApplied Intuition secured $600 million in Series F venture funding, with Kleiner Perkins, BlackRock, and CE-Ventures as key investors. Pending FinancingApplied Intuition’s CEO has identified an initial public offering as a short-term goal for the company, contingent upon favorable market conditions. |
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| 29 | Surge AI | $15.0B |
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Industry
Knowledge Management
Recent Deal
July 2025
Value Trend
Company DescriptionSurge AI provides a platform that uses human intelligence to create high-quality, annotated data for training advanced artificial intelligence models like large language models. Recent NewsIn April 2026, founder Edwin Chen was recognized as the youngest newcomer to the Forbes 400 as Surge AI reached an annualized revenue of $1.2 billion. The company previously faced a class action lawsuit in May 2025 regarding the alleged misclassification of its data annotators as independent contractors. Furthermore, leaked internal documents from July 2025 revealed the specific safety guidelines and restricted web sources used to train advanced artificial intelligence models. Recent FinancingThe company is in talks to raise venture funding from undisclosed investors. Pending FinancingSurge AI is reportedly in talks to raise approximately $1 billion in its first external funding round at a rumored valuation ranging from $15 billion to $25 billion. |
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| 30 | Nscale | $14.6B |
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Industry
AI Infrastructure
Recent Deal
March 2026
Value Trend
Company DescriptionNscale provides vertically integrated, renewable-powered data centers and specialized computing clusters designed to handle the massive processing requirements of large-scale artificial intelligence models. Recent NewsOn April 23, 2026, BT Group and Nscale announced a partnership to develop 14 megawatts of sovereign AI data center capacity across existing telecommunications infrastructure sites in the United Kingdom. This followed reports on April 9, 2026, that OpenAI paused the Stargate UK project, a major collaborative infrastructure initiative in which Nscale was a primary partner. On May 26, 2026, Nscale signed a power purchase agreement with Vattenfall to secure renewable energy for the first phase of its 230MW data center development in northern Norway. Recent FinancingNscale raised $2 billion in Series C funding and secured a $1.4 billion financing package with participation from Aker ASA, 8090 Industries, and Nvidia. Pending FinancingNscale is reportedly planning an initial public offering for the second half of 2026 and has hired Goldman Sachs and JPMorgan to prepare for the listing. |
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| 31 | Skild AI | $14.0B |
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Industry
Knowledge Management
Recent Deal
January 2026
Value Trend
Company DescriptionSkild AI develops a universal, adaptable AI brain that enables any robot to perform diverse tasks in the physical world. Recent NewsOn April 15, 2026, Skild AI acquired Zebra Technologies' Robotics Automation business and its Symmetry Fulfillment platform to integrate its foundation model into enterprise-scale warehouse infrastructure. The company partnered with ABB Robotics and Universal Robots on March 19, 2026, to deploy its omni-bodied robotic brain across industrial and commercial sectors. Additionally, on April 23, 2026, Skild AI became a founding member of the NVIDIA Cosmos Coalition to advance open world foundation models for physical AI. Recent FinancingThe company secured a $1.4 billion Series C funding round with major participation from SoftBank Group, NVentures (NVIDIA), and Macquarie Capital. |
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| 32 | Shield AI | $12.7B |
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Industry
Defense Technology
Recent Deal
March 2026
Value Trend
Company DescriptionShield AI develops artificial intelligence software and autonomous aircraft that enable drones and fighter jets to navigate and complete missions in environments where GPS and communications are unavailable. Recent NewsOn May 19, 2026, the Pentagon selected Shield AI to integrate its Hivemind autonomy software into the Low-Cost Uncrewed Combat Attack System program to enable intelligent drone swarming. Additionally, on April 20, 2026, the company was chosen by the U.S. Navy to compete for $800 million in task orders for maritime intelligence and surveillance services. Shield AI also expanded its global footprint on April 29, 2026, by opening a new office in New Delhi to strengthen its operations in India. Recent FinancingShield AI secured a $2 billion Series G funding round and preferred equity financing with participation from Advent International, JPMorgan Chase, and Blackstone. Pending FinancingShield AI has been provided a $250 million delayed draw facility by Blackstone to support its future growth. |
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| 33 | Labs Companies | $12.5B |
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Industry
Human-Enhancement Technology
Recent Deal
August 2025
Value Trend
Company DescriptionLabs Companies develops artificial intelligence and augmented reality technology designed to digitize and integrate sensory experiences, such as taste, into social networking platforms. Recent NewsNo major non-financing news within the last 12 months. Recent FinancingLabs completed Series Seed and Series Seed II funding rounds along with a separate research and development round, with participation from JetDebt Finance, Jet Investments Group, and JET Venture Capital. Pending FinancingLabs is reportedly in conversations for its upcoming Seed 3 and Series A financing rounds, targeting corporate venture capital firms and food and beverage brands. |
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| 34 | Clear Street | $12.0B |
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Industry
Capital Markets
Recent Deal
January 2026
Value Trend
Company DescriptionClear Street replaces fragmented, outdated capital markets infrastructure with a single, cloud-native platform that offers institutional clients real-time clearing, financing, and trading capabilities. Recent NewsOn May 14, 2026, Clear Street launched a new trading app that provides individual traders with the same institutional-grade infrastructure and AI-driven tools used by large firms. The company also established a strategic partnership with Kalshi on May 1, 2026, to offer regulated institutional access to prediction markets and event contracts. Earlier, on March 23, 2026, Clear Street expanded its unified platform to include institutional digital asset trading for cryptocurrencies and stablecoins. Recent FinancingClear Street's Series C financing totaled $135.39 million, with notable backing from Baillie Gifford, SBI Holdings, and BlackRock Inc. Pending FinancingClear Street has withdrawn its plans for an initial public offering as of February 2026 due to market volatility and concerns regarding the impact of artificial intelligence on the fintech sector. |
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| 35 | Airwallex | $12.0B |
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Industry
Financial Technology
Recent Deal
May 2026
Value Trend
Company DescriptionAirwallex provides a global financial platform that bypasses traditional banking systems to allow businesses to manage cross-border payments, multi-currency accounts, and expenses through its own proprietary infrastructure. Recent NewsOn May 27, 2026, Airwallex launched a new global billing solution designed to automate complex invoicing and subscription management for AI and software businesses. Reports from May 28, 2026, indicate the company is relocating more than 100 employees from its China offices to the United States and Singapore to enhance data security. Additionally, the company expanded its high-yield treasury offering to U.S. businesses on March 6, 2026, surpassing 1 billion dollars in global assets under administration. Recent FinancingAirwallex secured an undisclosed amount of venture funding in a round led by Addition. Pending FinancingAirwallex is reportedly aiming to be ready for an initial public offering in 2026, although the company has declined to comment on its current plans. |
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| 36 | OpenEvidence | $12.0B |
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Industry
Medical Information
Recent Deal
December 2025
Value Trend
Company DescriptionOpenEvidence is an artificial intelligence company that develops a medical search engine to assist physicians with clinical decision support. Recent NewsOn May 4, 2026, OpenEvidence and the American College of Obstetricians and Gynecologists announced a strategic collaboration to integrate evidence-based clinical guidance into the platform for ob-gyn care. Earlier, on March 31, 2026, the company partnered with Mount Sinai Health System to provide medical knowledge directly within electronic medical records, and on March 25, 2026, it launched Coding Intelligence to automate medical coding and improve reimbursement accuracy. Additionally, on March 10, 2026, the platform reached a milestone of one million clinical consultations between verified physicians and the AI system within a single 24-hour period. Recent FinancingOpenEvidence received $250 million in venture funding. |
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| 37 | Whatnot | $11.5B |
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Industry
Live Commerce
Recent Deal
October 2025
Value Trend
Company DescriptionWhatnot operates a live-stream shopping platform that lets users buy and sell collectibles and unique items in real-time auctions. Recent NewsOn May 28, 2026, Whatnot launched a direct integration with Shopify, enabling merchants to automatically synchronize product catalogs and inventory for live-streamed auctions. Additionally, in May 2026, the company entered a first-of-its-kind commercial partnership with the St Kilda Football Club to serve as the club's official and exclusive live shopping partner through the end of the 2026 season. Recent FinancingWhatnot secured $225.00 million in Series F venture funding from major investors including CapitalG, DST Global, and Andreessen Horowitz. Pending FinancingWhatnot plans to initiate a $126 million tender offer as part of its latest financing round, allowing select current investors to purchase shares from existing shareholders. |
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| 38 | Notion | $11.0B |
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Industry
Knowledge Management
Recent Deal
January 2026
Value Trend
Company DescriptionNotion is an AI-powered, all-in-one workspace that consolidates an organization's documents, projects, and knowledge base, allowing teams to manage all their work in one place. Recent NewsOn April 27, 2026, Notion introduced new database rollup formats for currency and percentages, following an April 24 update that enhanced navigation speed through breadcrumbs. During April 2026, the company also launched autonomous Custom Agents designed to automate workflows like task triaging and reporting across integrated tools such as Slack and Google Drive. These AI agents were made available for a free trial period running until May 3, 2026, to allow teams to test their autonomous capabilities. Recent FinancingA $270 million private tender offer for employee shares included investments from GIC, Sequoia Capital, and Index Ventures. Pending FinancingNotion is reportedly considering an initial public offering as early as the end of 2026. |
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| 39 | Harvey | $11.0B |
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Industry
Legal Tech
Recent Deal
February 2026
Value Trend
Company DescriptionHarvey develops specialized artificial intelligence systems that automate complex legal tasks like contract analysis, regulatory compliance, and litigation research to streamline professional workflows. Recent NewsOn May 29, 2026, law firms Shakespeare Martineau and Mayo Wynne Baxter announced the introduction of the Harvey AI platform to provide their professionals with AI-powered tools for research, drafting, and document analysis. Additionally, in early 2026, Harvey completed the integration of Hexus AI, a startup specializing in AI-driven enterprise legal tech tools, following an acquisition that occurred in late 2025. Recent FinancingHarvey secured $200 million in venture funding led by Goodwin Investments and Sequoia Capital, with participation from General Catalyst. |
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| 40 | ElevenLabs | $11.0B |
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Industry
AI Audio
Recent Deal
February 2026
Value Trend
Company DescriptionElevenLabs is an artificial intelligence company that develops models to create highly realistic, customizable human-like voices for content and interactive applications. Recent NewsElevenLabs introduced an initiative on May 19, 2026, to bring its voice AI technology into classrooms to support educational impact. On May 29, 2026, the company joined the Built in Europe campaign to promote regional technological sovereignty among leading startups. Additionally, the firm announced a partnership with the San Francisco Giants on April 6, 2026, to utilize its platform for fan engagement and audio content. Recent FinancingElevenLabs raised $500 million in Series D venture funding led by Sequoia Capital, with participation from AMP Coalition and Smash Capital. Pending FinancingElevenLabs is reportedly building toward an initial public offering with speculation pointing to a 2027 or 2028 timeline. |
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| 41 | Quantinuum | $10.8B |
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Industry
Quantum Computing
Recent Deal
November 2025
Value Trend
Company DescriptionQuantinuum uses trapped-ion quantum computing hardware and software to offer solutions for complex problems in chemistry, material science, and finance. Recent NewsOn May 20, 2026, Quantinuum partnered with bp to solve wave physics challenges and announced a collaboration with Synopsys on May 19 to advance industrial design. The company also expanded its partnership with BMW Group on May 5, 2026, and upgraded its quantum system for RIKEN on April 16, 2026, to scale quantum-supercomputing in Japan. Recent FinancingQuantinuum secured $838.85 million in Series B venture funding from NVentures, Cambridge Quantum Computing, and Honeywell. Pending FinancingQuantinuum has filed for an initial public offering to raise up to $1.05 billion and has signed a non-binding letter of intent for up to $100 million in federal funding under the CHIPS Act. |
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| 42 | Colossal Biosciences | $10.3B |
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Industry
De-extinction Genetics
Recent Deal
September 2025
Value Trend
Company DescriptionColossal Biosciences uses genetic engineering and reproductive technology to bring back extinct species and protect critically endangered ones. Recent NewsOn May 19, 2026, Colossal Biosciences announced it successfully hatched 26 healthy chickens using a proprietary artificial egg system, marking a significant milestone in its efforts to resurrect extinct bird species like the dodo and giant moa. The company also revealed on the same day that it is in the final stages of developing an artificial womb to support the gestation of large mammals. Additionally, on May 1, 2026, Colossal reported progress on its initiative to de-extinct the Blue Buck, an antelope that disappeared from southern Africa in the early 18th century. Recent FinancingColossal Biosciences secured $320 million in Series C venture funding, led by Thomas Tull, Mark Walter, and North Equity. |
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| 43 | WHOOP | $10.1B |
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Industry
Wearable Technology
Recent Deal
March 2026
Value Trend
Company DescriptionWhoop develops a screenless wearable device that continuously monitors physiological data like heart rate variability and sleep to provide users with personalized recovery and performance analytics. Recent NewsOn May 25, 2026, Whoop launched its next-generation wearables, Whoop 5.0 and the medical-grade Whoop MG, while introducing a new pricing model in Australia that decouples hardware costs from its subscription service. The company also announced an expanded integration with Strava on May 21, 2026, allowing users to share detailed muscle maps and lifting volume from their strength workouts. Additionally, in a May 30, 2026, interview, CEO Will Ahmed criticized the use of artificial intelligence as a scapegoat for corporate layoffs in the tech industry. Recent FinancingWhoop raised $575 million in a Series G funding round led by Collaborative Fund, with participation from Qatar Investment Authority and Mubadala Investment Company. |
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| 44 | Crusoe | $10.0B |
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Industry
AI Infrastructure
Recent Deal
October 2025
Value Trend
Company DescriptionCrusoe builds vertically integrated AI infrastructure by converting wasted natural gas into energy for high-performance computing clusters. Recent NewsOn March 27, 2026, Crusoe announced plans to build a 900 MW AI factory campus in Abilene, Texas, to support Microsoft's artificial intelligence infrastructure. The company also secured a major agreement with Form Energy on March 24, 2026, for 12 gigawatt-hours of iron-air battery storage and expanded its partnership with Redwood Materials to increase infrastructure density. Furthermore, on April 16, 2026, Crusoe contracted with PROENERGY to acquire 13 gas turbine generators to power its upcoming hyperscale data center projects. Recent FinancingCrusoe raised $1.38 billion of Series E venture funding led by Valor Equity Partners and Mubadala Capital, with participation from Nvidia. Pending FinancingCrusoe is rumored to be raising a pre-IPO funding round in the spring of 2026 at a $10 billion valuation and has expressed openness to a potential initial public offering in the future. |
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| 45 | Thinking Machines Lab | $10.0B |
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Industry
Artificial Intelligence
Recent Deal
June 2025
Value Trend
Company DescriptionThinking Machines Lab is building advanced artificial intelligence systems by integrating research and product development to ensure empirical and safety-focused deployment. Recent NewsOn May 21, 2026, Thinking Machines Lab unveiled Interaction Models, a new class of multimodal AI systems designed for continuous, real-time human interaction. On the same day, the company entered into a 471.7 million dollar service agreement with Boost Run Inc. for high-performance managed GPU computing and cloud infrastructure. Previously, on March 10, 2026, the lab announced a long-term, gigawatt-scale strategic partnership with NVIDIA to support its infrastructure requirements. Recent FinancingThe company raised $2 billion of seed funding in a deal led by Andreessen Horowitz, with participation from Nvidia and ServiceNow Ventures. Pending FinancingThinking Machines Lab is reportedly in talks to raise a new funding round that could value the company at between $50 billion and $60 billion. |
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| 46 | Mercor | $10.0B |
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Industry
Artificial Intelligence
Recent Deal
October 2025
Value Trend
Company DescriptionMercor operates an AI talent platform that utilizes human workers to train its machines by generating data, fundamentally changing how workforce tasks contribute to AI development. Recent NewsIn early April 2026, Mercor suffered a major data breach linked to a supply chain attack on the LiteLLM library, which led Meta to indefinitely pause its partnership with the company. By May 2026, the startup was hit with at least six class-action lawsuits in federal court alleging that the exposure of contractor personal data resulted from corporate negligence. Additionally, the firm launched Mercor Enterprise AI on March 26, 2026, to provide organizations with tools to build autonomous agents for internal data workflows. Recent FinancingMercor secured $350 million in Series C venture funding, with notable investors including Felicis, General Catalyst, and Benchmark Capital Holdings. Pending FinancingInvestors have reportedly offered to fund Mercor at a $10 billion valuation in a new $100 million financing round, though the company's CEO has dismissed claims that active discussions are occurring. |
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| 47 | Neuralink | $9.7B |
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Industry
Medical Devices
Recent Deal
January 2025
Value Trend
Company DescriptionNeuralink is developing implantable brain-machine interfaces designed to connect humans with computers and eventually facilitate direct neural communication. Recent NewsOn May 7, 2026, Neuralink announced it is developing a next-generation surgical robot capable of reaching any region of the brain with high precision to address a wider range of neurological conditions. Earlier in May 2024, the company received the FDA's Breakthrough Device Designation for its Blindsight implant, which aims to restore vision. Additionally, in March 2026, Neuralink shared progress on its PRIME Study, highlighting that its second participant is successfully using the Link implant to control digital devices. Recent FinancingRaised $650 million of Series E venture funding from Group 42 Holding, SaxeCap, and 1802 Ventures. |
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| 48 | Polymarket | $9.6B |
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Industry
Prediction Market
Recent Deal
March 2026
Value Trend
Company DescriptionPolymarket is a blockchain-based prediction market that allows users to bet on the outcome of real-world events, creating a real-time, useful measure of public belief on future outcomes. Recent NewsOn May 28, 2026, federal charges were unsealed against a Google software engineer for allegedly using confidential internal search data to net over $1.2 million in profits on Polymarket. This followed the arrest of a U.S. Army soldier in early May 2026 for similar insider trading involving classified information about a military operation in Venezuela. Additionally, on May 26, 2026, Spain's ministry of consumer rights blocked access to the platform as part of an investigation into whether it is operating without a required gambling license. Recent FinancingPolymarket raised a $2 billion strategic investment and $600 million direct cash investment with participation from Intercontinental Exchange, Founders Fund, and Blockchain Capital. Pending FinancingPolymarket is reportedly in early-stage discussions with investors to raise $400 million in a new funding round that would value the company at approximately $15 billion. |
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| 49 | Grafana Labs | $9.5B |
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Industry
Observability Platform
Recent Deal
March 2026
Value Trend
Company DescriptionGrafana Labs provides an open-source platform that allows organizations to aggregate, visualize, and analyze operational data from various databases to monitor the performance of their digital infrastructure. Recent NewsOn May 19, 2026, Grafana Labs confirmed that a cybercrime group, later identified as Coinbase Cartel, gained unauthorized access to its GitHub repositories and exfiltrated its codebase via a supply chain attack on the TanStack npm framework. The company detected the breach on May 11, 2026, and subsequently refused a ransom demand after confirming that no customer data or production systems were compromised. Additionally, on May 26, 2026, the company announced the general availability of new panel styling and copy-paste features across all editions of its platform. Recent FinancingGrafana Labs completed a $250 million Series E funding round, a $150 million tender offer, and a secondary share sale with participation from GIC, Ontario Teachers' Pension Plan, and Sapphire Ventures. |
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| 50 | Vercel | $9.3B |
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Industry
Web Development
Recent Deal
September 2025
Value Trend
Company DescriptionVercel is a cloud platform that simplifies and accelerates web development by providing infrastructure and tools for modern, high-performance websites and applications. Recent NewsOn May 29, 2026, the company introduced new security features to protect against token theft and improved environment variable management within its dashboard. Additionally, in early May 2026, researchers identified that cybercriminals were weaponizing Vercel’s v0 generative AI tool to create convincing phishing pages at scale. Recent FinancingThe company raised $300.00 million of Series F venture funding in a deal led by Enterprise Holding (Singapore), Accel, and GIC Private. Pending FinancingVercel is reportedly considering an initial public offering as its AI-driven revenue surges, though market conditions have currently slowed potential listing plans. |
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Data that informs the Disrupt 50 index is collected as of the last day of the previous month.
Metric definitions:
- Rank: Based on the most recently available post money value estimate.
- Move: The rank move from the previous month.
- Post Money: The most recently disclosed or estimated post money value based upon available information.
- Recent Deal: The most recent deal either publicly disclosed or announced.
- Value Trend: The trend in post money value. A down arrow suggests that the most recent round was a down round.
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Data Sources: S&P Global Market Intelligence and PitchBook Data, Inc. Data was also retrieved from various sources using Google Gemini.