The Disrupt 50

An index of the top private innovators shaping the future of tech and pushing the boundaries of human achievement.

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Innovator Spotlight: OpenAI

State of the Market

OpenAI is a pioneering artificial intelligence research organization founded to advance digital intelligence in ways that benefit humanity. Best known for its GPT language models and the widely adopted ChatGPT platform, the company recently converted its main entity into a for-profit benefit corporation in October 2025, shifting from its previous capped-profit structure while continuing to balance commercial pursuits with a mission to ensure safe AGI development. With recent expansions into enterprise solutions, OpenAI serves over 1 million businesses, delivering tools that integrate AI into workflows for measurable ROI.

OpenAI's disruptive advantage comes from its fast-paced development of multimodal AI. This is shown in the 2025 launch of ChatGPT Atlas, a web browser that integrates real-time AI assistance. It also includes projections for AI systems that could enable small scientific discoveries by 2026 and larger breakthroughs by 2028. Envisioning a future where AGI transforms industries from healthcare to finance, OpenAI is pushing boundaries amid financial headwinds, including anticipated losses through 2028 before profitability in 2030, while seeking U.S. policy support for data center expansions. Competitors like Anthropic, which eyes faster profitability, and tech giants Google and Meta are intensifying the race, steering the AI sector toward compute-intensive AGI pursuits that demand trillions in infrastructure investment and ethical safeguards.

Deal Metrics

Median

Recent Deal Size

$0.7B

Median

Raised to Date

$1.7B

Median

Time Between Financing Rounds

0.9 years

Average

Recent Deal Size

$1.7B

Average

Raised to Date

$5.2B

Average

Time Between Financing Rounds

1.2 years

Top Disrupt 50 Investors

1

Andreessen Horowitz

Menlo Park, CA

11 companies
2

Coatue Management

New York, NY

10 companies
3

1789 Capital

Palm Beach, FL

9 companies
4

Lightspeed Venture Partners

Menlo Park, CA

9 companies
5

Altimeter Capital Management

Menlo Park, CA

8 companies
6

General Catalyst

San Francisco, CA

8 companies
7

Nvidia

Santa Clara, CA

8 companies
8

Sequoia Capital

Menlo Park, CA

8 companies
9

BFA Global Investors

Sydney, Australia

7 companies

The Disrupt 50

Tap any company for additional details.

Rank Rank Move Company Post Money Expand row
1 OpenAI $500.0B
2 SpaceX $400.0B
3 Anthropic $183.0B
4 xAI $113.0B
5 Databricks $100.0B
6 Stripe $91.5B
7 Waymo $45.0B
8 Ripple $40.0B
9 Figure AI $39.0B
10 Safe Superintelligence $32.0B
11 Anduril Industries $30.5B
12 Scale AI $29.2B
13 Motional $28.2B
14 Ramp $22.5B
15 Epic Games $22.5B
16 Kraken $20.0B
17 Perplexity AI $20.0B
18 Deel $17.3B
19 Rippling $16.8B
20 Veeam $15.0B
21 Applied Intuition $15.0B
22 Surge AI $15.0B
23 Labs Companies $12.5B
24 Wiz $12.0B
25 Whatnot $11.5B
26 Quantinuum $10.8B
27 Colossal Biosciences $10.3B
28 Cognition $10.2B
29 Crusoe $10.0B
30 Thinking Machines Lab $10.0B
31 Sierra $10.0B
32 Mercor $10.0B
33 Anysphere $9.9B
34 Neuralink $9.7B
35 Harvey AI $9.3B
36 Gusto $9.3B
37 Vercel $9.3B
38 VAST Data $9.1B
39 Polymarket $9.0B
40 Altos Labs $8.8B
41 Cerebras Systems $8.1B
42 Reflection AI $8.0B
43 Flock Safety $7.5B
44 Glean $7.2B
45 PsiQuantum $7.0B
46 Groq $6.9B
47 Grafana Labs $6.6B
48 ClickHouse $6.4B
49 Plaid $6.1B
50 Redwood Materials $6.0B

Data that informs the Disrupt 50 index is collected as of the last day of the previous month.

Metric definitions:

  • Rank: Based on the most recently available post money value estimate.
  • Move: The rank move from the previous month.
  • Post Money: The most recently disclosed or estimated post money value based upon available information.
  • Recent Deal: The most recent deal either publicly disclosed or announced.
  • Value Trend: The trend in post money value. A down arrow suggests that the most recent round was a down round.

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Data Sources: S&P Global Market Intelligence and PitchBook Data, Inc. Data was also retrieved from various sources using Google Gemini.